A new role for the RNAi protein Dicer has been found in preserving genomic stability. Researchers discovered that Dicer helps prevent collisions during DNA replication by freeing transcription machinery from active genes. Without Dicer function, transcription and replication machinery collide, leading to DNA damage and massive changes across the genome - changes that are associated with aging and cancer.
A new role for the RNAi protein Dicer has been found in preserving genomic stability. Researchers discovered that Dicer helps prevent collisions during DNA replication by freeing transcription machinery from active genes. Without Dicer function, transcription and replication machinery collide, leading to DNA damage and massive changes across the genome - changes that are associated with aging and cancer.
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